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Unlock detailed insights into cellular interactions with ZEISS's advanced spatial biology imaging solutions. Perfect for translational research and immuno-oncology, this workflow integrates multiplex tissue imaging for scalable and reproducible results.

Transform Your Research with ZEISS Spatial Biology

Key Takeaways

  • Research focus: Multiplex tissue imaging for spatial biology.
  • Model system: Tissue samples with multiplex immunofluorescence.
  • Research goal: Enhance reproducibility in large cohort studies.
  • Presented by: ZEISS, highlighting biopharma applications.
  • Content type: Application Tutorial on imaging and analysis workflow.
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2 min read
5 μm FFPE section of mouse kidney simultaneously stained with 6 IF markers plus DAPI. Imaged on Axioscan 7 spatial biology for spatial omics applications

Unlock clarity in complexity and accelerate your spatial biology research. ZEISS solutions for spatial biology seamlessly integrate multiplexed tissue imaging and analysis into your workflows, enabling scalable, reproducible, and high-throughput spatial profiling. By visualizing cellular interactions in their native tissue context, our technologies empower researchers to gain deeper insights into disease mechanisms and transform the way pathology and translational science are approached.

Are you working in translational research, immuno-oncology, or a service lab seeking a high-throughput tissue imaging workflow that ensures accuracy and reproducibility across large cohorts?
The ZEISS tissue multiplexing workflow for biopharma, academic medical centers, and CROs scales spatial biology to routine histopathology settings. By integrating automated slide scanning, multiplex staining, and streamlined analysis, laboratories can generate rich biomarker data with high consistency and reproducibility across studies.

Standardized and automated methods ensure consistency across multi-site clinical studies and longitudinal projects. The workflow also streamlines analysis and reporting through integrated software, enabling researchers to evaluate multiple biomarkers simultaneously and translate data into actionable biological and clinical insights.

Diagram explaining the end-to-end spatial biology workflow starter bundle ​
  • Fluorescently labeled antibody reagents used for staining samples

    Our solution is compatible with a broad range of multiplex immunofluorescence reagents, giving users the flexibility to work with their preferred chemistries.​

  • High performance high-through slide scanner for fluorescence imaging

    Load the scanner with 100 samples and scan them in less than a day with unprecedented speed, fully automated and supported by AI-enabled tissue detection and high dynamic range imaging. Analyze up to eight biomarkers at the same time and generate highly reproducible data you can rely on. We offer complementary service solutions to integrate streamlined workflow solutions into pre-existing LIMS and IMS systems.​

  • Streamlined amd simplified user Interface optimized for routine user. The new assay manager allows for easy set-up of new imaging and analysis routines without the need for expert microscopy knowledge.

  • Mindpeak. AI-powered data analysis and image management platform Mindpeak. AI-powered data analysis and image management platform

    Generate actionable insights from your images, using our new spatial biology platform for fast, scalable, and effortless multiplexed IF image data analysis.​

  • ZEISS' spatial biology bundle has transformed the way we generate spatial phenotypic data for our clinical research.

  • ZEISS is addressing a key bottleneck in whole-tissue scanning through their workflow and we are benefitting from the efficiency gain.

  • project overview
  • project image overview ims
  • Screenshot of a Mindpeak project image overview named mIF Tumor Screen
    Screenshot of a Mindpeak project image overview named mIF Tumor Screen

Elevate your multiplexing IF and IHC workflows with ZEISS Axioscan 7 for Spatial Biology combined with the power of Mindpeak, leaders in the field of digital pathology. Our new Spatial Biology analytics platform enables effortless transition to cloud-based image analysis—giving researchers remote access to their images, project organization tools, and automated AI-driven workflows. Powered by Mindpeak’s foundation AI models for advanced image analysis, the system delivers robust results and standardized reporting, without the need for expertise and efforts to adjust or develop algorithms, while still offering the flexibilities to analyze a growing set of common biomarkers used in oncology and immuno-oncology including customizable phenotype definitions for precision in biomedical assays.​

https://www.zeiss.com/microscopy/us/applications/spatial-biology.html
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